Krauss has said she used to dislike working in the studio where she had to play the same song repeatedly, but has come to like studio work roughly the same as live stage performances. Her own favorite concert experiences include watching three Foreigner concerts during a single tour, a Dolly Parton concert, and a Larry Sparks concert. She appeared on Austin City Limits in 1992 and opened the show in 1995 with Union Station. The New Favorite tour, after AKUS' album of the same name, was planned to start September 12, 2001 in Cincinnati, Ohio, but was delayed until September 28 in Savannah, Georgia following the September 11 terrorist attacks Krauss also took part in the Down from the Mountain tour in 2002, which featured many artists from the O Brother, Where Art Thou. Down from the Mountain was followed by the Great High Mountain Tour, which was composed of musicians from both O Brother and Cold Mountain, including Krauss. She has also given several notable smaller performances including at Carnegie Hall (with the Grand Ole Opry), on Lifetime Television in a concert of female performers, on the radio show A Prairie Home Companion where she sang two songs not previously recorded on any of her albums, and a performance at the White House attended by then-President Bill Clinton and then-Vice President Al Gore.

Alison Krauss has won a record twenty-seven Grammy Awards over the course of her career as a solo artist, as a group with Union Station, as a duet with Robert Plant, and as a record producer. This is more than any other female artist and is the third most won by any artist overall. She overtook Aretha Franklin for the most female wins at the 46th Grammy Awards where Krauss won three, bringing her total at the time to seventeen (Franklin won her sixteenth that night), and performed with Sarah McLachlan. The Recording Academy (which presents the Grammy Awards) presented her with a special musical achievement honor in 2005. She has also won 14 International Bluegrass Music Association Awards, 8 Country Music Association Awards, 2 Gospel Music Association Awards,[citation needed] 2 CMT Music Awards, 2 Academy of Country Music Awards, and 1 Canadian Country Music Award. Country Music Television ranked Krauss 12th on their "40 Greatest Women of Country Music" list in 2002.

At the 76th Academy Awards in February 2004, where she performed two nominated songs from the Cold Mountain soundtrack, Alison Krauss was chosen by Hollywood shoe designer Stuart Weitzman to wear a pair of $2 million 'Cinderella' sandals with 4½ inch clear glass stiletto heels and two straps adorned with 565 Kwiat diamonds set in platinum. Feeling like a rather unglamorous choice, Krauss said, "When I first heard, I was like, 'What were they thinking?' I have the worst feet of anybody who will be there that night!" In addition to the fairy-tale-inspired shoes, Weitzman outfitted Krauss with a Palm Trēo 600 smartphone, bejeweled with 3,000 clear-and-topaz-colored Swarovski crystals. The shoes were returned, but Krauss kept the crystal-covered phone. Weitzman chose Krauss to show off his fashions at the urging of his daughters, who are fans of Krauss' music.